One truth many people are not aware of is the fact that certain drugs used in the treatment of breast cancer can cause the ovaries of a woman into early 'set back' within months of receiving treatment. This could lead to a kind of menopause known as Medical Menopause. Fifty percent of women younger than 35 who have cancer drugs, cytoxan, methotrexate, fluorouacil go into menopause, as do about 80 percent of women between 35 to 44 years of age and nearly 100 percent of women over 45. Occassionally, the drug-induced menopause is only temporary.
Interestingly, cancer drugs-induced menopause usually presents with sever symptoms due to dramatic drop in estrogen production. Hot flushes can get worse when tamoxifen or other anti-estrogen therapies are added after chemotherapy. Chemotherapy makes symptoms of menopause worse due to its blocking actions on estrogen receptors in the body.
In summary, cancer drugs can induce menopause and even worsen some of the symptoms of menopause like;
Irregular Menstruation: A preempting signs of menopause whereby sometimes period may come on the 21st day, others 26th, 30th etc
Amenorrhea: The cessation or stoppage of menstrual flow for a period of at least six months in a woman above 40 years of age without evidence of pregnancy.
Hot Flushes: Characterized by sweating, redness of skin, internal heat and restlessness occuring mainly on the upper part of the body.
Genital/Breat Athrophy: This is characterised by vaginal dryness, weakening and shrinking of the muscles of vagina and womb.
Dyspareunia: Painful sexual intercourse resulting from vaginal dryness.
Infection and Urinary incontinence: Urine leakage or the inability to control urine flow.
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